B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...

A recent study by Vanderbilt Health researchers has revealed a greater, detrimental role for B lymphocytes (B cells) in the ...

Abnormal B cells dictate HIV-specific responses Early treatment linked with greater capacity to maintain pretreatment levels of B-cell response to virus. The cells that produce antibodies to HIV and ...

Researchers from the School of Veterinary Medicine and Perelman School of Medicine have found that YY1 knockout pro-B cells can generate T lineage cells helping B cells produce antibodies. Development ...

Zenas BioPharma announced advancements in the clinical development of obexelimab, a novel CD-19 x FcγRIIb inhibitor targeting B cell function, with key trial results expected in 2025. The Phase 2 ...