(L) Corresponding author Thirumala-Devi Kanneganti, PhD, St. Jude Center of Excellence for Innate Immunity and Inflammation director and Department of Immunology vice chair and (R) and first author ...

Researchers found that activating the STING pathway with an experimental agonist reduced meningioma growth, triggered inflammatory tumor cell death, and lowered tumor volume and mortality in mice, ...

Autophagy is indispensable for maintaining hepatocyte integrity, metabolic homeostasis, and survival. While several autophagy ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital published today in ...

Researchers in Japan have identified a striking new way immune cells strip DNA out of dying neighbors, a process they call ...

Programmed cell death (PCD) stands at the forefront of innovation in experimental pharmacology and drug discovery, providing fundamental insights into ...

RIPK1 inhibition reduced inflammation and keratinocyte cell death in lichen planus and CLE models. Could this be a new treatment approach? Read more.

Mitochondria are involved in apoptosis, necrosis, pyroptosis, and iron death. At present, the research on cell apoptosis is relatively thorough, and the mechanism of mitochondria in it has also been ...

Scientists link TMC protein membrane disruption to hearing loss, showing how mutations, drugs and noise trigger hair cell ...