Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable ...

Thyroid development represents a complex orchestration of cellular migration, differentiation and folliculogenesis, all of which are tightly regulated by an interplay of signalling pathways and ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the ...

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Researchers have identified Nr1h2, a critical transcription factor essential for early embryo development. Their findings enhance our understanding of gene regulation during blastoid formation and ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development—including the production ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development - including the ...

Although embryonic stem cells (ESCs) have been successfully derived from mice and rats, efforts to establish chimeric and germline-competent ESC lines in species beyond rodents have been unsuccessful.