New scientific methods could one day render animal studies—the standard in research laboratories for more than 100 ...

The tumor microenvironment (TME) is a metabolically dynamic niche where cancer cells and immune cells interact to influence tumor progression and immune ...

Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

In some mammals, the timing of the normally continuous embryonic development can be altered to improve the chances of survival for both the embryo and the mother. This mechanism to temporarily slow ...

The field of cancer biology has recently recognized the significance of immunogenic cell death (ICD), a process by which dying cells emit alarm ...

Cells have a variety of processes and pathways that can repair damage, remove trash and debris, and boost healing. Scientists have now discovered a novel process in which cells eliminate stuff, and ...

Discover the challenges of acute myeloid leukaemia linked to inflammatory cell death and the quest for effective therapies.

A research team at The University of Osaka has found a novel pathway for depositing CENP-A into vertebrate centromeres, which ...

A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply ...