Embryonic development is a meticulously orchestrated process in which spatial and temporal cues guide cell fate determination and tissue patterning. Central to this process is morphogen signalling – a ...

Embryonic development is a finely orchestrated process in which a single cell differentiates into the myriad specialised tissues that comprise a fully formed organism. Central to this process are ...

Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is ...

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the "dark side" of the ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...

In the earliest hours after fertilization, an embryo takes its first steps toward becoming a living organism by shedding maternal control and activating its own genetic program. This critical process, ...

Cell division is an essential process for all life on earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive – particularly for egg-laying ...

In A Nutshell Egg geometry drives development: The curved shape of a zebrafish egg causes unequal cell divisions, creating larger cells near the animal pole and smaller cells at the margin—a size ...

Researchers have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization. This is ...

Research led by the SickKids Research Institute in Toronto and the University of Pennsylvania, has found that immune-related ...

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), ...