Identifying functional effects of noncoding variants is a major challenge in human genetics. To predict the noncoding-variant effects de novo from sequence, we ...

Figure 1: Convergence hypotheses and genomic distribution of support. Figure 2: Relationship between strength of convergence signal and adaptive selection. To explore more fully the relationship ...

Two examples of the same molecule represented in sequence, image and graph formats are provided for direct comparison. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...