Medically reviewed by Michael MacIntyre, MDKey TakeawaysProzac and Zoloft are similar selective serotonin reuptake inhibitors (SSRIs) prescribed for anxiety and depression.Prozac is FDA-approved for ...

This description of my feelings makes sense, given how Zoloft works: serotonin, the happy hormone, leaves the synapse, and Zoloft acts like a bouncer that won’t allow it to reenter. This keeps the ...