Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...

The Abu-Remaileh Lab published an atlas of proteins, found in lysosomes across different brain cell types, to advance research on neurodegenerative diseases.

CHICAGO (CBS) -- Lysosomes – membrane-bound structures within each cell of humans and all animals – are sometimes known as the cells' "garbage disposals" or "cellular janitors." The structures are ...

Collaborative research at the University of Cincinnati has developed a new probe to better study cells that has already led to new knowledge about certain cellular processes. UC’s Jiajie Diao, PhD, ...

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break ...

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...

Transmission electron microscopic image of an isolate from the first U.S. case of COVID-19, formerly known as 2019-nCoV. The spherical viral particles, colorized blue, contain cross-section through ...

C-terminal fragments of amyloid precursor protein have been blamed for endolysosomal dysfunction in Alzheimer’s disease. Now, scientists led by Wim Annaert at KU Leuven, Belgium, claim that’s because ...

The retromer complex controls protein sorting, transport, and disposal via the endolysosome system. It goes awry in neurodegenerative diseases, but how so remains unclear. Metabolism breaks down in ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.