FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

第五届单细胞与空间组学论坛近日，安徽医科大学第一附属医院与美国哈佛医学院第二大附属教学机构布里格姆女子医院研究团队合作共同在期刊《Advanced Science》上发表了研究论文，题为“TRIM47 Regulates Energy ...

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...

Researchers have uncovered how metabolic reprogramming contributes to renal fibrosis in IgG4-related disease (IgG4-RD), a systemic immune-mediated disorder. The review, published in a leading journal, ...

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer ...

Integrative analysis of immune ecotypes in skin cancers highlights metabolic reprogramming and macrophage polarization as key ...

Chronic activation of the stress protein ATF6α promotes aggressive liver tumors by rewiring glucose metabolism and ...

The integration of single-cell and spatial transcriptomics with advanced metabolic profiling tools has revolutionized the ...

Researchers have discovered a way to make the immune system's T cells significantly more effective at fighting cancer. By blocking a protein called Ant2, they were able to reprogram how these cells ...