Migrating cells must determine where to form a front end and a back end. A gradient in contact sites between the cell membrane and an organelle called the endoplasmic reticulum (ER) is generated by a ...

Synthetic hydrogel-based assay to study 3D confined cell migration. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adm9195 Eukaryotic cells—that is, cells with a nucleus—possess an astounding ...

How do cells move from A to B through our body to build functional tissues? And how is this process regulated? The answers to these questions are essential – for example, for our understanding of how ...

In wound healing, immune response, and cancer metastasis, cells migrate through the body—often squeezing through narrow, confined spaces. Together with experimental collaborators, Professor David ...

Ever wondered how the different cells in our body communicate with each other to fulfill their different roles-be it cells repairing a tissue injury or immune cells moving towards an invading pathogen ...

In wound healing, immune response, and cancer metastasis, cells migrate through the body – often squeezing through narrow, confined spaces. Together with experimental collaborators, Professor David ...

Oxidative stress kills wandering melanoma cells by a process called ferroptosis, in which polyunsaturated fatty acids in the cancer cell membrane react with iron. “It’s like a grease fire starting in ...

Scientists are looking for answers about how these confounding trips, known as metastases, occur throughout the human body Illustration of a human cancer cell Amber Dance, Knowable Magazine Back in ...

CD8+ T cells accumulate in atherosclerotic plaques. Researchers identify a crucial signaling pathway -- with therapeutic potential. CD8+ T cells accumulate in atherosclerotic plaques. LMU researchers ...