Magnetic nanoparticles engineered T cells inside living mice and guided them into solid tumors, achieving over 90% tumor ...

Cancer-killing T cells have been programmed to have two levels of specificity. First, the T cells have been equipped with a receptor sensitive to a protein that is found only in central nervous system ...

Shares of Hoth Therapeutics Inc (NASDAQ:HOTH) advanced 3.6% in premarket trading on Wednesday after the clinical-stage ...

Metacaspases, ancestral homologues of the caspase family, are pivotal cysteine proteases found in a wide range of unicellular organisms, including yeasts, algae, and phytoplankton. These enzymes ...

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, ...

Cells have the remarkable ability to initiate their own death through a mechanism called programmed cell death, also known as apoptosis. Apoptosis contains sophisticated signalling pathways and ...

Different types of programmed cell death. This picture summarizes the different pathways of programmed cell death (Note: ROS: reactive oxygen species). By unveiling the complex interactions between ...

A team of researchers at the University of Cologne’s Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...