The monocyte activation test (MAT) represents a significant advancement in pyrogen detection, offering a robust, in vitro alternative to traditional animal-based assays such as the rabbit pyrogen test ...

MAT test potential replacement for the traditional rabbit pyrogen testing (RPT) for vaccines The implementation of the MAT reduces the use of animals for vaccine safety testing Article published in ...

The global pyrogen testing market is expected to reach a value of USD 1.9 billion by 2025, according to a new report by Grand View Research, Inc. Increasing demand for therapeutic drugs including ...

The European Pharmacopoeia recently announced plans to replace the rabbit pyrogen test by 2026, with a clear preference for the MAT. PYROSTAR Neo+, a recombinant protein-reagent for the detection of ...