ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo
Chromatin endogenous cleavage (ChEC) uses fusion of a protein of interest to micrococcal nuclease (MNase) to target calcium-dependent cleavage to specific genomic loci in vivo. Here we report the ...
An AI system developed by UK-based company DeepMind has achieved the long-sought-after goal of accurately predicting the shape of proteins from their sequence alone, a key part of understanding how ...
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