A collection of protocols covering a variety of methods to achieve super resolution in microscopy to include structured illumination, single-molecule fluorescence and localization-based approaches.

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Researchers used consumer-grade 3D printers to create sub-$1 optical lenses that enable super-resolution nanoscale biological ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Advanced light microscopy techniques are giving scientists a new understanding of human biology and what goes wrong in diseases Katarina Zimmer, Knowable Magazine Innovative techniques are helping ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Researchers at Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) have developed an innovative microscopy ...

A project at the University of Strathclyde has now shown that consumer-grade 3D printers and low-cost materials can be used to produce multi-element optical components that enable super-resolution ...

Overcoming the resolution limit in a light microscope of around half a wavelength of light (about 250 nanometers) is one of the most significant developments in optics. Due to the wave nature of light ...

Current calibration methods rely on artificially constructed DNA structures or specific cellular features, each with significant drawbacks. DNA-based rulers require complex chemical synthesis and only ...