In mammals and other eukaryotes most of the genome is transcribed in a developmentally regulated manner to produce large numbers of long non-coding RNAs (ncRNAs). Here we review the rapidly advancing ...

It is not currently possible to determine the precise structure of every protein-coding gene in a complex, eukaryotic genome. However, the past 10 years have seen steady progress in the accuracy and ...

Liver damage typically progresses through four stages — inflammation, fibrosis, cirrhosis, and end stage liver disease (ESLD) — with worsening scarring that reduces liver function. Liver failure can ...