Replicability is a subtle and nuanced topic, especially when discussed broadly across scientific and engineering research. An attempt by a second researcher to replicate a previous study is an effort ...

College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada ...

Production of value-added chemicals in living cells holds promise to reduce the need for oil and divert to more sustainable production methods. The list of chemicals that can be produced through ...

The structure of life emerged from randomness. This is attributed to selection by molecular Darwinian evolution. This study found that random templated ligation led to the simultaneous elongation and ...

As the ongoing outbreak in the Democratic Republic of Congo illustrates, Ebola virus disease continues to pose a significant risk to humankind and this necessitates the continued development of ...

Understanding the function of stochasticity in biological systems has been a long-standing challenge 1,2,3. Two main principles have been recognized. First, stochastic algorithms allow simpler genetic ...

Inference and conclusions drawn from model fitting analyses are commonly based on a single "best-fitting" model. If model selection and inference are carried out ...

Riboswitches are short RNA sequences for ligand-dependent modulation of gene expression in cis. This study demonstrates that an artificial riboswitch, a ligand-dependent self-cleaving ribozyme ...

Objectives To assess quality of reporting of sample size calculation, ascertain accuracy of calculations, and determine the relevance of assumptions made when calculating sample size in randomised ...