Mir195 enables Ebf1-deficient hematopoietic progenitor cells to mature into B cells, suggesting some miRNA can substitute for transcription factors in differentiation.

Hirschsprung’s disease (HSCR) is characterized by congenital absence of ganglion cells in the gastrointestinal tract, which leads to impaired defecation, constipation and intestinal obstruction. The ...

ABSTRACT: Objective: This study aimed to identify differentially expressed microRNAs (miRNAs) using microarray and to predict special target genes using bioinformatics methods in the neonatal rat ...

Abstract: MicroRNAs (miRNAs) are reported to play essential roles in cancer initiation and progression and microarray technologies are intensively applied to study the miRNA expression profile in ...

Background: Exercise is recognized for its broad health benefits, influencing various physiological processes, including the behavior of adipose tissue macrophages (ATMs). While existing studies ...

Building on on the observation of an increase in miR-182-5p in diabetic patients, the authors investigated the role of miR-182-5p and its target gene LRP6 in dysregulated glucose tolerance and fatty ...

OBJECTIVES: The aim of this study was to compare the expression levels of serum miRNAs in diabetic retinopathy and type 2 diabetes mellitus. METHODS: Serum miRNA expression profiles from diabetic ...

We and others have found inconsistencies in miRNA expression levels between different array platforms, highlighting the current technical challenges and limitations of miRNA studies. A recent, ...