CD3: A Golden Target in Bispecific Antibody Therapeutics
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CD3: A Golden Target in Bispecific Antibody Therapeutics
CD3 is a multi-subunit complex expressed on the surface of all mature T cells, composed of four peptide chains: γ, δ, ε, and ζ. Among these, the γ, δ, and ε chains belong to the immunoglobulin superfamily, each containing an extracellular immunoglobulin domain. The ζ chain forms a dimer, and its cytoplasmic domain carries three ITAM ...
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