The Plug Talk on Instagram: "A tweaker is a slang term commonly used to describe a person who is under the influence of stimulant drugs—especially methamphetamine—and is experiencing intense restlessness, paranoia, hyperactivity, or compulsive behavior as a result. It can also more broadly refer to someone behaving nervously or erratically, even without drugs involved, but the word is most often tied to meth use and the behaviors that come with it."